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Proprietary blends such as Bremetide and Erexafil are formulated based on pharmacokinetic properties and clinical development findings reported significantly in placebo controlled studies, including those published in J Sex Med, Int J, and expert opin emerg drugs literature

Outcome of patients following hepatic resection for metastatic cutaneous and ocular melanoma

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This polyspecificity distinguishes Melanotan-2 from the next generation of analogs:PT-141 / bremelanotide is MC4R preferential, afamelanotide (Scenesse) is MC1R selective

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4 Trauma and post-inflammatory pigmentation Any repeated micro-trauma to a specific point on the lip (a habitual lip-biting spot, friction from a tooth, a healed cold sore, an old burn from hot food or drinks) can trigger localized post-inflammatory hyperpigmentation that stabilizes into a melanotic macule